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Leadership TeamGenstruct has assembled an impressive list of industry leaders to manage the company. Our leadership team hails from both top tier pharmaceutical companies as well as successful entrepreneurial organizations, and boasts a combined experience of nearly 100 years.David de Graaf, Ph.D. - Chief Scientific Officer Christopher Z. Thomajan - Chief Financial Officer Louis Latino - EVP, Sales & Marketing Dexter Pratt - VP, Innovation & Knowledge Julian Ray, Ph.D. - SVP, Technology & Engineering Renée Deehan Kenney, Ph.D. - Senior Director, Scientific Research & Operations Andrea L. Matthews - VP, Commercial Operations  Chief Scientific Officer Dr. de Graaf joined Genstruct in 2010 after spending 2 years at Boehringer-Ingelheim as vice president of biotherapeutics and integrative biology. In this role, Dr. de Graaf developed a world class biotherapeutics research organization, using Computational and Systems Biology to develop a pipeline with new targets as well as specify the desired properties of each drug to achieve efficacy and safety in human settings; this group became the template for extensive further growth in therapeutics research. In 2005 Dr. de Graaf joined Pfizer as its first director of systems biology. Dr. de Graaf provided a strategy to implement systems biology as a way to transform drug research for Pfizer, and led a team at the Pfizer Research and Technology Center (RTC), working on applying systems biology approaches to issues across the Pfizer pipeline. Before joining Pfizer, Dr. de Graaf spent 5 years at AstraZeneca, where he built the first systems biology team, focused on modeling and simulation in both the UK and the US. Previously, his work with Prof. Doron Lancet at the Weizmann Institute of Science in Israel, used computational and wet biology approaches to try to deconvolute odorant binding to olfactory receptors. At Prof. Eric Lander's suggestion, Dr. de Graaf relocated to the Center for Genome Research at the Whitehead/MIT, where he set up a group working on target validation, and worked in close collaboration with colleagues at Millennium, Bristol-Myers Squibb, and Affymetrix. Dr. de Graaf completed his undergraduate work at the University of Utrecht, in the Netherlands, where he obtained a Master's degree in EvolutionaryGenetics. His doctoral work, under the supervision of Professor Igor Roninson at the University of Illinois at Chicago, focused on the multi-drug resistance pump p-glycoprotein and its transport mechanisms. At this time, Dr. de Graaf became involved in some of the earliest functional genomics approaches using gene fragment libraries in retroviral vectors. His postdoctoral work focused on the pharmacogenomics of olfaction. to top  Chief Financial Officer Mr. Thomajan has 18 years of experience in a variety of industries, including Biotechnology, Investment Banking, Software, Internet Services, and Telecomm. He has extensive experience in raising debt and equity, has been involved in numerous M&A transactions, and has managed the Operations of several start-up companies during rapid revenue growth. He was a Founding Partner of America’s Growth Capital, a boutique investment bank focused on emerging growth technology companies, and was the early stage CFO/VP Operations for Asurion Corporation which has grown to over $1 billion in revenues. He was also the CFO for a pioneering Internet company, Delphi Internet Services, which was acquired by News Corporation in 1993. Mr. Thomajan received a B.A. from Dartmouth College and an M.B.A. from Columbia University. to top EVP, Sales & Marketing Mr. Latino joined Genstruct in 2008, bringing almost 30 years of senior sales management and direct sales experience. Prior to joining Genstruct, he was VP of North America, Life Sciences Sales and Support for Accelrys, Inc., a developer of a broad range of technologies, including computer-aided-molecular-design and scientific business intelligence software. He honed his life sciences expertise as VP of Worldwide Sales for Geneformatics and as a regional sales manager for Biosym Technologies. Mr. Latino has also held sales positions at other technology companies, including Superscape Group, Mitchell Management Systems and BIW Cable Systems. Mr. Latino earned his bachelor’s degree in chemistry from Boston College. to top  VP, Innovation & Knowledge Mr. Pratt began consulting for Genstruct in 2002, and joined the company as its director of Biological Systems Modeling in 2003. While with Genstruct, Mr. Pratt has served as a technical team leader, software developer and platform architect, while also performing as biology project leader, team member and principal investigator for Genstruct’s internal and partnered projects. Mr. Pratt has an extremely strong background in artificial intelligence. He was a member of the research staff at the M.I.T. Artificial Intelligence Laboratory, where he worked on the team developing LISP hardware prototypes. In 1981, he joined LISP Machine, Inc., where he became the director of the User Interface Group and participated in the design and implementation of both hardware and software, including the development of a 1,000 chip LISP processor. In 1989, Mr. Pratt joined the CYC project, where he spent seven years developing novel knowledge representation systems and inference mechanisms for a groundbreaking, large-scale common sense reasoning system. Mr. Pratt has extensive startup experience, having served as the CTO for two internet media companies: Webkick and CineMetrix, where he was the technical architect of their respective platforms. Mr. Pratt received his undergraduate degree in chemistry from Yale University. to top SVP, Technology & Engineering Dr. Ray has more than 18 years of experience in designing, developing and deploying innovative solutions to challenging technology and information management systems problems. Prior to joining Genstruct, Dr. Ray was the chief technology officer (CTO) at auctionPAL, a venture-backed, technology-enabled, business-to-consumer services company. He co-founded C2GLogistics, an Internet startup providing a suite of web-based services and mobile applications with a large customer base in the life sciences industry. Dr. Ray has also served as a senior software scientist at Intergraph Corporation and director of the Transportation Research Center at the University of Tennessee. He has presented more than 30 technical papers at professional and academic conferences and authored a dozen peer-reviewed articles in academic publications and conference proceedings. Dr. Ray received his Ph.D. and M.S. degrees from the University of Tennessee and his B.S. from Reading University in the United Kingdom. to top Senior Director, Scientific Research & Operations Dr. Kenney is responsible for managing the company’s scientific research programs and is instrumental in supporting its business development efforts. With Genstruct since 2006, she has led nine successful commercial projects, including a collaboration with Sirtris Pharmaceuticals, which received the 2008 Bio-IT Best Practices Award in the area of Drug Discovery & Development. Dr. Kenney studied bioengineering at the University of Pennsylvania and received her Ph.D. in molecular and cell biology from the University of California, Berkeley. The focus of her dissertation research was on the understanding of mechanisms of chromosome condensation and sister chromatid cohesion in spindle assembly and cancer. to top  VP, Commercial Operations Ms. Matthews joined Genstruct in 2003 and has been integrally involved in driving the progress of the company’s scientific and technology development by managing its pharmaceutical research projects. As director, Alliance Management, Ms. Matthews is responsible for coordinating the alliance activities of the company, managing various business activities within Genstruct’s consulting organization and supporting the sales organization. With her expertise in project management, alliance management, scientific research and sales, Ms. Matthews will focus on project identification definition, as well as project scoping and project management. Ms. Matthews received her B.A. cum laude in biochemistry and molecular biology from Boston University and was named one of Mass High Tech's "People to Watch Under 30" in 2007. to top |
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